Skin Changes in Iatrogenic Cushing’s Syndrome: A Detailed Case Analysis

Nanda Earlia; Mimi Maulida; Vella Vella; Aldilla  Pradistha; Wizurai Wisesa; Abdur Razaq; Tubagus Pasca Faiz Ikram; Muhammad Zahrul Rahmatillah; Bianda Sabrina Farsa; Fajri Alghani

doi:10.60084/ijcr.v2i2.243

Authors

Nanda Earlia Department of Dermatology and Venereology, Faculty of Medicine Universitas Syiah Kuala, Banda Aceh 23111, Indonesia; Department of Dermatology and Venereology, Dr. Zainoel Abidin Hospital, Banda Aceh 23111, Indonesia
Mimi Maulida Department of Dermatology and Venereology, Faculty of Medicine Universitas Syiah Kuala, Banda Aceh 23111, Indonesia; Department of Dermatology and Venereology, Dr. Zainoel Abidin Hospital, Banda Aceh 23111, Indonesia
Vella Vella Department of Dermatology and Venereology, Faculty of Medicine Universitas Syiah Kuala, Banda Aceh 23111, Indonesia; Department of Dermatology and Venereology, Dr. Zainoel Abidin Hospital, Banda Aceh 23111, Indonesia
Aldilla Pradistha Faculty of Medicine, Universitas Syiah Kuala, Banda Aceh 23111, Indonesia
Wizurai Wisesa Faculty of Medicine, Universitas Syiah Kuala, Banda Aceh 23111, Indonesia
Abdur Razaq Faculty of Medicine, Universitas Syiah Kuala, Banda Aceh 23111, Indonesia
Tubagus Pasca Faiz Ikram Faculty of Medicine, Universitas Syiah Kuala, Banda Aceh 23111, Indonesia
Muhammad Zahrul Rahmatillah Faculty of Medicine, Universitas Syiah Kuala, Banda Aceh 23111, Indonesia
Bianda Sabrina Farsa Faculty of Medicine, Universitas Syiah Kuala, Banda Aceh 23111, Indonesia
Fajri Alghani Faculty of Medicine, Universitas Syiah Kuala, Banda Aceh 23111, Indonesia

DOI:

https://doi.org/10.60084/ijcr.v2i2.243

Keywords:

Iatrogenic Cushing's syndrome, Corticosteroid, Erythematous purulent lesions, Atrophic striae

Abstract

Cushing's syndrome can lead to various skin complications. Iatrogenic Cushing's syndrome is a condition caused by excessive exogenous glucocorticoid exposure. This case report presents a patient with a history of Cushing's syndrome and long-term corticosteroid use who developed multiple skin manifestations. A 20-year-old male presented with erythematous purulent lesions on the face, neck, chest, and back. Concurrently, the patient developed purplish-red striae on the chest, abdomen, arms, and legs. Physical examination revealed erythematous nodules and pustules, along with atrophic striae. Laboratory tests showed leukocytosis with a left shift and hypokalemia. Radiological investigations revealed lumbar spondylosis and cardiomegaly. The patient was treated with a combination therapy, including topical and systemic medications, and showed significant improvement in skin lesions. This case highlights the importance of a comprehensive evaluation for patients presenting with unusual skin lesions. A thorough history, physical examination, and laboratory investigations are crucial to identify underlying conditions and initiate appropriate treatment.

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