Regeneration of the Anterior Talofibular Ligament Following PRP Therapy: A Case Report with Serial MRI Evidence

Zhi Huang See; Sing Wei Low; Seu Kean Tan

doi:10.60084/ijcr.v3i2.352

Authors

Zhi Huang See Department of Sports Medicine, Faculty of Medicine, Universiti Malaya, Lembah Pantai, 50603, Wilayah Persekutuan Kuala Lumpur, Malaysia
Sing Wei Low Department of Family Medicine, Faculty of Medicine and Health Sciences, Universiti Putra Malaysia, 43400, Serdang, Selangor, Malaysia
Seu Kean Tan Department of Radiology, Hospital Seberang Jaya, Jalan Tun Hussein Onn, 13700, Seberang Jaya, Pulau Pinang, Malaysia

DOI:

https://doi.org/10.60084/ijcr.v3i2.352

Keywords:

Platelet rich plasma, Lateral ankle sprain , Anterior talofibular ligament, Regeneration

Abstract

Lateral ankle sprain (LAS) is one of the most common lower limb injuries, particularly in individuals involved in sports and recreational activities. The anterior talofibular ligament (ATFL) is the structure most frequently affected. Platelet-rich plasma (PRP) has shown potential in promoting tissue regeneration and accelerating healing. We report a case of a grade 3 ATFL tear treated with a single PRP injection combined with functional rehabilitation therapy, with serial MRI scans demonstrating ligament continuity and clinical recovery. This case highlights PRP hypothesized as a useful adjunct treatment for LAS involving ATFL injury when combined with functional rehabilitation, as it may promote ligamentous healing, improve short-term symptoms, and potentially reduce the long-term risk of developing chronic ankle instability.

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