The Potent Antimicrobial Spectrum of Patchouli: Systematic Review of Its Antifungal, Antibacterial, and Antiviral Properties


  • Pati Kemala Graduate School of Mathematics and Applied Sciences, Universitas Syiah Kuala, Banda Aceh 23111, Indonesia
  • Rinaldi Idroes Department of Pharmacy, Faculty of Mathematics and Natural Sciences, Universitas Syiah Kuala, Banda Aceh 23111, Indonesia; Department of Chemistry, Faculty of Mathematics and Natural Sciences, Universitas Syiah Kuala, Banda Aceh 23111, Indonesia
  • Khairan Khairan Department of Pharmacy, Faculty of Mathematics and Natural Sciences, Universitas Syiah Kuala, Banda Aceh 23111, Indonesia; Pusat Riset Obat Herbal Universitas Syiah Kuala, Banda Aceh 23111, Indonesia
  • Muliadi Ramli Department of Chemistry, Faculty of Mathematics and Natural Sciences, Universitas Syiah Kuala, Banda Aceh 23111, Indonesia
  • Trina Ekawati Tallei Department of Biology, Faculty of Mathematics and Natural Sciences, Sam Ratulangi University, Manado, Indonesia
  • Zuchra Helwani Department of Chemical Engineering, Riau University, Pekanbaru 28293, Indonesia
  • Sunarti Abd Rahman Department of Chemical and Process Engineering Technology, Universiti Malaysia Pahang Al-Sultan Abdullah, Lebuhraya Persiaran Tun Khalil Yaakob, 26300 Gambang, Kuantan, Pahang, Malaysia



Pogostemon cablin, Essential oil, Patchouli alcohol, Patchouli oil


ntention towards natural essential oils from medicinal plants has increased rapidly over the past decade as these oils have antimicrobial and antioxidant properties against various chronic diseases. One essential oil source with antimicrobial properties is the essential oil from Pogostemon cablin (Blanco) Benth. This review aims to provide information on using patchouli oil as an antimicrobial against bacterial, fungal, and viral pathogens in the last five years. There were 37 articles found in the PUBMED database by June 15, 2023. After searching, 6 of them were duplicates. A total of 2 papers were inaccessible, 4 were not research articles, and five were excluded because they were irrelevant to the scope of this study. This review shows that research related to patchouli as an antimicrobial in the last five years involves Pogostemon cablin leaf samples as silver nanoparticle bioreductors. Patchouli oil is used in membrane, nanocomposite film, and starch hydrogel manufacturing. Patchouli oil is a prestigious antimicrobial agent because it can fight numerous pathogenic microbes from bacteria, fungi, and viruses.


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How to Cite

Kemala, P., Idroes, R., Khairan, K., Ramli, M., Tallei, T. E., Helwani, Z., & Rahman, S. A. (2024). The Potent Antimicrobial Spectrum of Patchouli: Systematic Review of Its Antifungal, Antibacterial, and Antiviral Properties. Malacca Pharmaceutics, 2(1), 10–17.