A Review of the Ethno-dentistry Activities of Calotropis gigantea


  • Diana Setya Ningsih Graduate School of Mathematics and Applied Sciences, Universitas Syiah Kuala, Banda Aceh 23111, Indonesia; Department of Dental Material, Faculty of Dentistry, Universitas Syiah Kuala, Banda Aceh 23111, Indonesia
  • Ismail Celik Department of Pharmacy, Erciyes University, Turkiye
  • Abdul Hawil Abas Faculty of Bioscience Engineering, Ghent University, Gent 9000, Belgium
  • Boy Muhclis Bachtiar Department of Oral Biology, Faculty of Dentistry, Universitas Indonesia, Jakarta, Indonesia
  • Pati Kemala Graduate School of Mathematics and Applied Sciences, Universitas Syiah Kuala, Banda Aceh 23111, Indonesia
  • Ghazi Mauer Idroes Department of Occupational Health and Safety, Faculty of Health Sciences, Universitas Abulyatama, Aceh Besar, Indonesia
  • Nur Balqis Maulydia Graduate School of Mathematics and Applied Sciences, Universitas Syiah Kuala, Banda Aceh 23111, Indonesia




Calotropis gigantean, Ethno-dentistry, Caries, Periodontitis, Wound healing


Calotropis gigantea is a medicinal herb that thrives in arid climates. All parts of this plant are rich in secondary metabolites, which are very beneficial for health. Phytochemicals of this plant include flavonoid, alkaloids, steroids, cardiac glycosides, and terpenoids, which have a wide range of pharmacological effects. The potential of metabolit compound from C. gigantea can be used in dental treatment. This review describes the potential use of C. gigantea in ethno-dentistry, specifically as anti-caries, soft tissue inflammation (periodontitis and gingivitis), degenerative diseases (tumor/cancer), and wound healing. This review provides general perspectives and basic literature on the use of C. gigantea in the field of etno-dentistry.


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How to Cite

Ningsih, D. S., Celik, I., Abas, A. H., Bachtiar, B. M., Kemala, P., Idroes, G. M., & Maulydia, N. B. . (2023). A Review of the Ethno-dentistry Activities of Calotropis gigantea. Malacca Pharmaceutics, 1(1), 8–15. https://doi.org/10.60084/mp.v1i1.31